Thrombophilia is logically associated with miscarriages and has less or no implication in difficulty of conception.

Thrombophilia increases the possibility of endometrium vessel clotting at the implantation site resulting in obstruction of blood flow in the vessels and inadequate supply of nutrients to the developing embryo. Histological examination of products of conception show endometrial blood vessel congestion, rupture of wall lining and hemorrhaging followed by necrosis at the implantation site. This is mainly attributed to defective coagulation factors due to genetic predisposition to thrombophilia inherited from one or both parents of the female partner. Thrombophilia is treated by administration of anticoagulants.

Thrombophilia testing during infertility investigation and pregnancy.

While there is a large number of conventional biochemical tests and genetic coagulation factor mutation screening, especially for infertility diagnosis we believe that the most important is a combination of 2 or more of the following tests depending on each case and on the medical and family history of the prospective mother.

Available Tests Code Price  
Genetic Screening Panels For Thrombophilia
Hereditary thrombophilia screening panel (5 MUTATIONS) HTS1021 200,00 €
Factor V Leiden mutation, MTHFR C677T mutation, MTHFR A1298C mutation, PAI-1 (plasminogen activator inhibitor activator), Factor II Prothrombin (PT) G20210A mutation
Single Factor Genetic Screening
Factor V Leiden mutation HTS1001 80,00 €
Factor II Prothrombin (PT) G20210A mutation HTS1003 80,00 €
MTHFR C677T mutation HTS1005 80,00 €
MTHFR A1298C mutation HTS1006 80,00 €
PAI-1 (plasminogen activator inhibitor activator) mutation HTS1007 80,00 €