When it comes to fertility, a thorough investigation should leave no stone unturned. At FERTILYSIS, we place emphasis on addressing the potential role of male factor in unexplained infertility and we aim to bring fatherhood closer by investigating male fertility from the privacy of your home.
Does your microbiome damage your sperm?
Let’s talk male infections.
Did you know that bacterial infections in the male accessory sex glands can negatively impact semen quality? These semen infections can reduce sperm count, motility, and morphology, while also causing sperm DNA damage through inflammation and oxidative stress. These microbes can even adhere to sperm and release substances that affect sperm motility or trigger cell death.
Beyond affecting your fertility, male infections can disrupt your partner's reproductive health by impacting her endometrial and vaginal microbiome.
Key Questions to Consider:
• Do you have a high DFI (DNA Fragmentation Index)?
• Have you had a history of Prostatitis?
• Have you received abnormal sperm analysis results (low count, poor motility, or abnormal morphology)?
• Has your partner had infections detected through female microbiome testing?
DNA Fragmentation Analysis: A Critical Test for Male Infertility
Let’s talk Sperm DNA integrity.
While a traditional semen analysis is the gold standard for evaluating male fertility, it doesn't provide the full picture. This is where DNA Fragmentation Index (DFI) testing plays a vital role. DFI analysis assesses the integrity of sperm DNA, which is crucial for determining male fertility potential. High sperm DNA fragmentation levels often correlate with poor semen quality, abnormal sperm structure, and idiopathic infertility.
Key Questions to Consider:
- Do you have borderline semen analysis results?
- Have you faced repeated IVF, IUI, or ICSI failures despite multiple attempts?
- Had tests shown infections or dysbiosis in your semen microbiome?
- Do you suffer from varicocele, a condition commonly linked to male infertility?
Male Infertility is more common than you think. Let’s start talking about it!
Male infertility is a common issue, affecting 40%–50% of couples facing infertility, with bacterial and virus infections of the genitourinary tract contributing to 15% of cases!
You can't call it "checked" if you haven't covered everything!
If you’re checking off your fertility checklist, make sure to include testing focused on the male factor.
At Fertilysis, we aim to bring fatherhood closer by thoroughly evaluating every aspect of male fertility, from DNA fragmentation to Microbiome health, semen infections or Semen Fish Chromosomal Analysis which focuses on detecting spermatozoa with an abnormal chromosomal make up. This test is particularly useful in cases of male infertility or recurrent pregnancy loss, where chromosomal abnormalities in sperm may contribute to reproductive problems. Especially in cases of significant oligozoospermia (low sperm count) where assisted reproductive techniques like in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) are used, FISH analysis provides valuable information about the genetic integrity of sperm, helping fertility specialists understand the potential risks of using it for fertilization of egg. By identifying aneuploid sperm (sperm with abnormal chromosome numbers), healthcare providers can make informed decisions about the most appropriate fertility treatments for couples facing infertility or pregnancy loss related to sperm chromosomal abnormalities.
