Vaginal Inflammation Index: A promising marker for the prevention of infertility?
Cytokines and chemokines of the female reproductive tract are released to induce an innate immune inflammatory response to sexually transmitted pathogens and resident members of the pathogenic vaginal microbiota. Excess levels of inflammation may lead to cellular damage and increased mucosal vulnerability to sexually transmitted and viral infections.
FERTILYSIS Inflammation Index
320€
Self-collectable, non-invasive & painless sampling method
No doctor's referral
2 vaginal swabs
Storage in the freezer. Shipping at ambient temperature
Results in 10 business days
Time matters! FastTrack Results.
Your time matters because your journey should always be a priority, every step of the way.
Fertilysis FastTrack Results stand as a commitment to remove barriers and redefine timelines. Get your test results in 5 working days expedited, from the day your sample reaches us, instead of the standard processing time.
250€
WE GOT YOU.
The FERTILYSIS Inflammation Index test is an innovative solution for the early detection of local inflammation of the vaginal epithelium used in conjunction with the Fertilysis Full Microbiome or the Fertilysis Vaginal Microbiome tests.
Activation of local immunity is a marker for microbiome dysbiotic disorders leading to infertility, implantation failure, chemical pregnancies and recurrent early pregnancy loss, as well as pregnancy complications including premature rupture of the membranes and premature birth.This test allows us to assess the state of the local (mucosal) immunity by analyzing expression levels of key genes of the immune response, the assessment of local cytokine profile and the ratio of pro-inflammatory to immunosuppressive cytokines, as a measure of local inflammation. Compared to the traditional methods for indirectly diagnosing local inflammation, the FERTILYSIS Inflammation Index test is more sensitive, and capable of detecting an inflammatory reaction at the initial stage, before an increase in the number of leukocytes, at an early stage of clinical manifestations.
Consider Fertilysis Inflammation index:
For women actively trying or planning to conceive, or undergoing preparation for IVF, and for women experiencing symptoms consistent with lower genital tract inflammation, bacterial vaginosis or vaginitis, we recommend further analysis and monitoring of the female genital tract by a Full Female Microbiome testing or traditional infection testing for the diagnosis and treatment of vaginal and uterine infections and endometritis and subsequent treatment/correction of detected infections/dysbiosis.
HOW IT WORKS.
Place your order online and get the FERTILYSIS box delivered at your home.
Follow our instructions to collect your samples and ship them back to us for analysis.
Receive your easy to understand results including treatment suggestions in just a few days via email.
Is your infertility really ‘’unexplained’’ or are you still undiagnosed?If you have been struggling with infertility and haven’t been getting convincing answers, chances are you are still missing a piece of the puzzle.
Did you receive treatment? Retest to confirm.
Retesting is essential for evaluating the effectiveness of your treatment and making necessary adjustments. It allows us to determine if the treatment was effective or needs to be repeated. Through careful reevaluation, we ensure that your personalized treatment plan remains effective.
320€
FERTILYSIS Inflammation index
STILL HAVE QUESTIONS?
These our the most common questions regarding this panel.
If you have more, please refer to our Q&A page.
The Inflammation Index is not included in the FERTILYSIS Female Microbiome: Full. You will need to order it separately.
The innate immune response can play a significant role in triggering infection-associated infertility and recurrent pregnancy loss (RPL). At FERTILYSIS we an innovative method to analyze the expression patterns of local inflammatory biomarkers of the lower genital tract. The resulting immunological profile can be used to assess the presence or absence of inflammatory reaction in the vagina and can be used as a diagnostic criterion for resolving discrepancies between laboratory data and clinical manifestations, as well as for choosing effective therapy. There is emerging evidence which shows that timely detection of local inflammation in patients at high risk of preterm delivery, can help to expedite adequate measures aimed to prolong their pregnancies.
The full version of our Female Microbiome panel, investigates both uterine and vaginal microbiomes, providing a full view on the female microbiome status. It allows easy and early detection, diagnosis & treatment of Endometritis, Vaginitis, Bacterial Vaginosis & Microbiome Dysbiosis, all of which have been strongly associated with female reproductive system pathologies & infertility, RIF, RPL, chemical pregnancies and serious complications of the 2nd & 3rd trimesters. It detects 27 pathogens (STIs, fungi & normal microflora) and includes an extended virus panel detecting CMV, EBV, HSV-1, HSV-2, and HHV-6.
Absolutely! Our tests are accessible worldwide, allowing you to conveniently perform them from the comfort of your home, regardless of your location. We ship worldwide!
